Is Follow-Up Needed After Leg Pain Treatment? Major joints of the leg include the hip, knee, and ankle, but the small joints in the feet and. How to Get Relief From Foot Pain Caused by Standing 10 Hours per Day. by JON Cross your foot over the other leg's knee while seated. Available at your local drug or grocery store, compression socks provide pain relief and prevent fluid collection in your legs, ankles and feet. Leg pain may be caused by neurological and musculoskeletal issuesl. Studies have shown that high intensity nerve stimulation may help treat chronic pain. Most people with nerve pain say medication provides only partial relief. Exercise also promotes blood flow to the nerves in the legs and feet. Hot-and cold-water therapy can be effective in treating foot pain. The hot treatment will promote blood flow, and the cold treatment will reduce inflammation.